Mar 8, 2022
Click here to
subscribe to Premium
The pathogenesis of obesity is clearly complex. And the need to
have a comprehensive model to explain this pathogenesis is
important.
One such model, termed the Energy Balance Model, has
largely been the consensus paradigm of obesity scientists to this
point. Specifically, a
recently published paper in the American Journal of
Clinical Nutrition by Dr. Kevin Hall and his colleagues outlined
the various nuances of the model, as well as common misconceptions
about the model.
However, there are others who propose that this is not the correct
model of obesity, but rather that obesity pathogenesis can be
better explained by a model called the Carbohydrate-Insulin Model
(CIM) of obesity.
While this model has been proposed in various forms over the past
couple of decades, the most recently published revision/update of
this model was that put forward by Dr. David Ludwig and colleagues,
in a
Perspective published also in the AJCN, in December of
2021.
In this episode, Dr. Kevin Hall (lead
author of the paper mentioned above) and Dr. Stephan
Guyenet are on the podcast to discuss the debate
surrounding these two models. Specifically, the discussion will
focus in on the Hall et al. (2022) and Ludwig et al. (2021) papers,
as well as previous work leading up to both.
Click here to
access show notes for this episode
Click here to subscribe to Premium