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Sigma Nutrition Radio

Apr 14, 2026

This episode examines what we actually know (and importantly, what we do not know) about diet in relation to gallstones and gallbladder conditions. Much of the public-facing guidance around gallstones focuses on “avoiding fatty foods”, yet Dr. Angela Madden explains that this long-standing practice sits on...


Apr 7, 2026

In this episode, Danny answers questions submitted by Premium subscribers.

Questions Answered in This Episode:

  1. [00:05:13] Is eating too early (relative to chronotype) metabolically problematic?
  2. [00:16:55] Can plant-based diets reverse cardiovascular disease?
  3. [00:32:54] Are multivitamins useful insurance, or a waste...


Mar 31, 2026

“The more we learn about the world, and the deeper our learning, the more conscious, specific, and articulate will be our knowledge of what we do not know, our knowledge of our ignorance. For this, indeed, is the main source of our ignorance — the fact that our knowledge can be only finite, while our ignorance...


Mar 24, 2026

This episode examines whether unprocessed red meat has a causal role in (1) type 2 diabetes risk and intermediate measures of glucose intolerance (insulin resistance, beta cell dysfunction, glycemic markers) and (2) cardiovascular disease (CVD) risk.

While there is commonly observed risk signal from...


Mar 17, 2026

This episode examines how exercise and nutrition interact to influence glycaemic control, with particular focus on the postprandial period (i.e., the hours after eating) and on “time-efficient” exercise strategies such as low-volume interval training.

Dr. Jenna Gillen outlines the physiological basis for why...